Controlling genome editing with nanomagnets | NextBigFuture.com
Date | 16th, Nov 2018 |
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Source | NextBigFuture - Scientific News Websites |
DESCRIPTION
A moth-infecting virus and nanomagnets could be used to edit defective genes that cause diseases like sickle cell, muscular dystrophy and cystic fibrosis. Above -Rice University bioengineers use a magnetic field to activate nanoparticle-attached baculoviruses in a tissue. The viruses, which normally infect alfalfa looper moths, are modified to deliver gene-editing DNA code only to cells that are targeted with magnetic field-induced local transduction. Courtesy of the Laboratory of Biomolecular Engineering and Nanomedicine Rice University bioengineer Gang Bao has combined magnetic nanoparticles with a viral container drawn from a particular species of moth to deliver CRISPR/Cas9 payloads that modify genes
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